Simon studied medicine at the University of Sheffield before specializing in psychiatry. Simon has an interest in transcultural psychiatry, having worked as a doctor overseas in Northern Uganda. He now works in psychedelic research, with a focus on ayahuasca and has spent the last five years conducting research into the use of ayahuasca in the Peruvian Amazon. He also works as a psychiatrist at The Maudsley Hospital in South London, as well as working as a Senior Research Associate at King’s College London looking at the use of psilocybin in treatment-resistant depression. He is currently completing a PhD looking at the the use ayahuasca in the Amazon and associated mental health outcomes.